منابع مشابه
The NPC, in detail
JCB • VOLUME 179 • NUMBER 7 • 2007 1328 The NPC, in detail T he nuclear pore complex (NPC) is a huge cylindrical assembly that transports material to and from the nucleus. In a biological tour de force, researchers have determined the positions of all 456 proteins of the NPC, providing structural insights of unprecedented detail. Among other discoveries, Svetlana Dokudovskaya, Liesbeth Veenhoff...
متن کاملVoting rule FI Gaps FP TOS PC CEV 1 TOS 1 Gap TTO BTO Plurality P NPC NPC NPC NPC P P NPC P NPC 2 - Approval P NPC NPC NPC NPC P P NPC P NPC
In bribery an external agent tries to alter the outcome of an election by changing some voters’ votes. Usually, when investigating bribery problems, full information is assumed, i.e., that the manipulative agent knows the set of candidates, each voter’s votes and the voting rule used. In this paper, we formally introduce different structures of partial information, we show the connections betwe...
متن کاملRNA Export through the NPC in Eukaryotes
In eukaryotic cells, RNAs are transcribed in the nucleus and exported to the cytoplasm through the nuclear pore complex. The RNA molecules that are exported from the nucleus into the cytoplasm include messenger RNAs (mRNAs), ribosomal RNAs (rRNAs), transfer RNAs (tRNAs), small nuclear RNAs (snRNAs), micro RNAs (miRNAs), and viral mRNAs. Each RNA is transported by a specific nuclear export recep...
متن کاملBuilding and breaking the NPC
alcium fluctuations in the bottom layer of a platelet mass are propagated upwards to determine the size of a blood clot, or thrombus, according to results from Nesbitt et al. presented on page 1151. Platelets adhere to substrates in the vessel wall through receptors such as GPIb and certain integrins. Initial receptor engagement stimulates Ca 2 ϩ spikes in the platelets that lead to firm, perma...
متن کاملGoing their own way in the NPC
Going their own way in the NPC T here’s more than one way to pass through a nuclear pore, as Terry and Wente show. Different cargos follow different routes through the channels, suggesting a new mechanism for regulating import and export. A nuclear pore is a bit like a high school hallway, with molecules and their carriers crowding through in both directions. As they make the crossing, carriers...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1797rr2